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Arginine-rich peptides - cell transmission carrier of gold n

date:2010-11-15 17:14
Changchun Institute of Applied Chemistry State Key Laboratory of Electroanalytical Chemistry, Sun Linlin and other researchers successfully developed the arginine-rich peptides - synthesis of gold nanoparticles cell transmission carrier met
Changchun Institute of Applied Chemistry State Key Laboratory of Electroanalytical Chemistry, Sun Linlin and other researchers successfully developed the "arginine-rich peptides - synthesis of gold nanoparticles cell transmission carrier method." Recently,Copper Chromite(CC), the results of the State Intellectual Property Office of the invention patents.
 
According to experts, bio-hybrid molecules and gold particles because of their good biocompatibility, with unique optical properties of cells can be real time and dynamic observation of the characteristics,CAS 12018-10-9, is considered to be material to achieve the transmembrane extracellular transmission is an excellent carrier. However, in these studies mainly use the polymer to stabilize the gold nanoparticles, combined with the signaling molecule, synthetic process is often very complex, requiring a longer reaction time, and difficult to combine various elements to achieve multi-functional. The National Natural Science Foundation of the strong support of Changchun Applied Chemical Institute researchers used peptide surface modification, the cell transfer to achieve the peptide - synthesis of gold nanoparticles.
 
Proved that the results of the peptide chain using gold nanoparticles stable and functional,copper chromium, with multiple conventional chemical modification methods, synthesis method is simple - no special equipment and response procedures simple, shorter time; detection means simple - ordinary optical microscope can be observed,copper chromate, to achieve high throughput detection of samples; the synthesized peptides - cell membrane transport of gold nanoparticles to achieve high efficiency, and by changing the delivery and stability of the peptide chain can control the ratio of peptide carrier transmission efficiency.